Publications

2026

Reprogramming the post-resection niche of primary malignant bone tumors: Biological opportunities, engineering limits and translational requirements of magnesium-based implants
Yu Sun, Shengzhi Liu, Heike Helmholz, Shanshan Liang, Olga Will, Björn Wiese, Lukas Nolte, Farhad Haj Mohamad, Monika Luczak, Domonkos Tolnai, Sven Tomforde, Jan-Bernd Hövener, Regine Willumeit-Römer
Journal of Magnesium and Alloys, in Press, 2026



Braided endovascular implants for intracranial aneurysms: mechanics, hemodynamics, and clinical translation
Ratnadeep Pramanik, Duygu Dengiz, Mariya S. Pravdivtseva, Martin Frank, Ivo Steinbrecher, Prasanth Velvaluri, Matthias Mayr, Philipp Berg, Sylvia Saalfeld, Naomi Larsen, Olav Jansen, Alexander Popp
arXiv preprint: Computational Physics, 2026


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Aneurysm Location Classification from 3D Point Clouds
Tameem Jahangir, Georg Hille, Sylvia Saalfeld
Conference Paper: Deutsche Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V. (CURAC) 2026

Clinical outcome prediction of Contour Neurovascular System treatment based on pre-treatment geometric and hemodynamic characteristics
Fina Gießler, Anna Bernovskis, Franziska Gaidzik, Jana Korte, Philipp Berg, Sönke Peters, Naomi Larsen, Sylvia Saalfeld
International Journal of Computer Assisted Radiology and Surgery, 2026,

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Hemodynamic Impact of Treatment-Induced Morphological Changes in Intracranial Aneurysms Treated with the Contour Neurovascular System: A Pilot In Silico Study
Anna Bernovskis, Fina Gießler, Philipp Berg, Franziska Gaidzik, Sylvia Saalfeld, Naomi Larsen, Philipp Berg
Brain Sciences, Neurosurgery and Neuroanatomy, 2026, 16(8), 830

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Contact-resolved deployment of the Contour Neurovascular System in patient-specific intracranial aneurysms
Ratnadeep Pramanik, Fina Gießler, Martin Frank, Ivo Steinbacher, Matthias Mayr, Sylvia Saalfeld, Alexander Popp
arXiv preprint: Computational Physics, 2026

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AI-Powered Hemodynamic Feature Selection and Prediction of Intracranial Aneurysm Wall Enhancement
Fina Gießler, Philipp Berg, Naomi Larsen, Sylvia Saalfeld
Journal of Flow Visualization and Image Processing, to appear, 2026

Morphological Stability of Intracranial Aneurysms and the Contour Neurovascular System: A Longitudinal Analysis
Lena I. Spitz, Jana Korte, Franziska Gaidzik, Naomi Larsen, Daniel Behme, Bernhard Preim, Sylvia Saalfeld
Cardiovascular Engineering and Technology, to appear, 2026

Mechanical study of NiTi intrasaccular aneurysm implants with flaps
Duygu Dengiz, Prasanth Velvaluri, Patrick Grotemeyer, Olav Jansen, Eckhard Quandt

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An ontology-based description of nano computed tomography measurements in electronic laboratory notebooks
F. Kirchner, D.C.F. Wieland, S. Irvine, S. Schimek, J. Reimers, R. Aversa, A. Boubnov, C. Lucas, S. Flenner, I. Greving, A. Lopes Marinho, T. M. Wong, R. Willumeit-Römer, C. Eschke, B. Zeller-Plumhoff

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Evaluating flow modulating treatment response in intracranial aneurysms using black-blood MRI in vitro
Mariya S. Pravdivtseva, Hivnu Toraman, Jana Korte, Franziska Gaidzik, Oluwabusayo A. Oni, Philipp Berg, Prasanth Velvaluri, Lana Bautz, Fritz Wodarg, Jan-Bernd Hövener, Olav Jansen, Naomi Larsen
Nature - Communication Medicine, 2026,

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Morphological factors and device deformation associated with recurrence in intracranial aneurysms treated with the contour neurovascular system
Naomi Larsen, Fritz Wodarg, Johannes Hensler, Karim Mostafa, Sönke Peters, Mariya Pravdivtseva, Sylvia Saalfeld, Friederike Gärtner
Journal of Neuroradiology, 2026,

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A 3D-1D-0D multiscale model of the neuro-glial-vascular unit for synaptic and vascular dynamics in the dorsal vegal complex
Alexander Hermann, Tobias Köppl, Andreas Wagner, Arman Shojaei, Barbara Wohlmuth, Roland Aydin, Christian Cyron, Roustem Miftahof
Journal of Mathematical Biology, 2026, 92(3): https://doi.org/10.1007/s00285-025-02317-7

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2025

A Helping Hand: A Survey About AI-Driven Experimental Design for Accelerating Scientific Research
Lukas Nolte, Sven Tomforde
Appl. Sci., 2025, 15(9):5208https://doi.org/10.3390/app15095208

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Feedback-guided Dataset Shaping for Automated Downstream Task Optimization
Lukas Nolte, Marten Finck, Sven Tomforde, Sören Pirk
Conference Paper: GI/ITG International Conference on Architecture of Computing Systems (ARCS) 2025

Real Super-Resolution for Proximal Femur: Enhanced Computation of Structural Bone Metrics from Clinical CTs
Niklas Koser, Marten Finck, Felix von Brackel, Benjamin Ondruschka, Sören Pirk, Claus-Christian Glüer
Conference Paper: Conference Proceedings: Proceedings of Medical Image Computing and Computer Assisted Intervention (MICCAI) 2025
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FemoraLyze: A Modular Framework for Proximal Femur Analysis
Marten Finck, Niklas Koser, Jan-Bernd Hövener, Claus-Christian Glüer, Sören Pirk
Conference Paper: Medical Imaging with Deep Learning (MIDL) 2025
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Preliminary In Vivo and Ex Vivo Assessment of MRI Artifacts from Biodegradable Mg-10Gd Implants: Implications for Alloy Design and Imaging Protocol Optimization.
Yu Sun, Aaron Diercks, Olga Will, Heike Helmholz, Berit Zeller-Plumhoff, Jan-Bernd Hövener, Regine Willumeit-Römer
Conference Paper: 27th annual meeting of the German-Austrian-Swiss section of the International Society of Magnetic Resonance in Medicine (DACH-ISMRM) 2025
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Optimization of Laboratory Infrastructure and Surgical Workflow in Preclinical Rodent Bone Research: An Underreported Barrier to Reproducibility
Yu Sun, Olga Will, Heike Helmholz, Chuchu Li, Haoyi Qiu, Kaya Waldhausen, Sara Alzaanin, Catriona Eschke, Berit Zeller-Plumhoff, Rachel W. Li, Stanislav Gorb, Jan-Bernd Hövener, Regine Willumeit-Römer
European Cells & Materials, 2025